Background: Bacterial injections are Life-threatening complications in uremic children. Early diagnosis is mandatory but very dilJ'tcult. because currently applied laboratory parameters may be affected by the underlying disease. the uremia, or the r..aemodialysis (HD).
Objectives: Evaluation oJthe diagnostic value ojserum procalcitonin (PCT) as an indicc;ttor ojsystemic bacterial injection in HD children.
I Study Design: This cross-sectional short-term study wciS' conducted on 33 children agedfrom 7-15 (mean = 9.1 ± l.8 years). 23 were males and 10 were females, they undergo intermittent HD. Also 30 apparently heruthy controls ojsame age group were recmite.d into the study, Cases are class!fi.ed into 2 groups. Group I: (injection +ve); include 15 patients with evidence ojsystemic bacterial irifection. Group H: (injection -vej: include 18 patients without evidence ojsystemic bacterial injection. For all cases blood samples beJore HDJor determining CRP. CBC. fL-6. PCT. albumin
and renalfunction testes. Results: PCf and CRP in group-I are significantly higher than group II while IL-6 and WBCs were elevated in both groups. per demonstrated higher sensitivity, specificity, positive and negative prediction values than CRP, IL-6 and WBCs. Further more. PCT serum levels were positively correlated with CRP. IL-6 and "VVBCs values. where it was negatively correlated with albumin and haemoglobin ualues. Conclusion: Procalcitonin (PCT) seems to be C', novel diagr.ostic indio
Ade1 Shebl, et aL.
cator ojsystemic bacterial injection in haemodialysis children. Additional investigations are needed to understand its synthesis and prognostic value. |
