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Dr. Abdelmotaal Abdelmajeid El-Shiekh Abdelmotaal Abdelmajeid :: Publications: |
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| Title: | Synthesis and Investigation of Mass Spectra and Antimicrobial Activity of Some Azoles and Azines Based on (QUINOLINE-8-YLOXY) ACETOHYDRAZIDE |
| Authors: | Abdelmotaal Abdelmajeid*, Aly A.Aly, M. S.Amine and Ahmed A. Ghith*. |
| Year: | 2016 |
| Keywords: | quinoline, 8-yloxy acetohydrazide, quinoline-8-yloxy methyl oxadiazole acetohydrazide, thiazole, oxazole, triazole, pyridazine, phthalazine and antimicrobial activity |
| Journal: | Int. J. Nano. Chem. |
| Volume: | 2 |
| Issue: | 2 |
| Pages: | 37-45 |
| Publisher: | NATURAL SCIENCE PUBLISHER |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Abdelmotaal Abdelmajeid El-Shiekh Abdelmotaal Abdelmajeid_INT J OF NANO CHEM..pdf |
| Supplementary materials | Not Available |
| Abstract: |
A new Azoles and Azines as pyrazole, thiazole, oxadiazole, triazole, thiadiazole, pyridazine and phthalazine based on quinolone moiety efficiently synthesized via simple and efficient chemical reactions of quinoline-8-yloxy acetohydrazide and quinolone-8-yloxy methyl oxadiazole acetohydrazide with electrophilic reagents in base medium using simple techniques and reagents. The structures of the new synthesized products were deduced based on their analytical, spectral data and by using the fragmentation pattern as a tool for supporting the chemical structures. In addition, the biological activity of the synthesized compounds as antimicrobial and antifungal were screened. |
