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Dr. Ahmed Alshenawi :: Publications: |
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| Title: | Synthesis And Antimicrobial Activity Of N-{4-[3-(4-Chlorophenyl)-Ethylene
Oxide-Carbonyl]-Phenyl}-2-(1,1,3-Trioxo-1,3-Dihydro-Benzo[D]Isothiazol-2-Yl)-
Acetamide |
| Authors: | A.I.El-Shenawy, A.A.Aly* |
| Year: | 2004 |
| Keywords: | Not Available |
| Journal: | Chemistry: An Indian Journal |
| Volume: | 15 |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Ahmed Alshenawi_My paper published in indian Journal.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Epoxide (2) was used to synthesize a number of new condensed and noncondensed heterocyclic systems. Thus, reaction of epoxide (2) with amines, hydrazines, active methylene compounds and Friedel-Craft s have been studied. On the other hand, epoxide (2) reacted with Grignard reagents and afforded (7a,b). However, epoxide (2) condensed with thiourea and glycine gave oxazolinethione and 2-morpholinone derivatives (8) and (9), respectively. Also, epoxide (2) reacted with acetic acid and gave (10). Action of different nitriles with epoxide (2) gave the hydroxy amide derivatives (11a-c), which underwent cyclization and afforeded 2-oxazoline derivatives (12a-c). ’ |
