| Abstract |
Objective: Comparing the recurrence rate of limbal auto graft transplantation versus single intraoperative subconjunctival Bevacizumab injection after surgical removal of the primary Pterygium.
Design: This is a randomized case controlled clinical study of fifty eyes of fifty patients complaining of primary pterygium of variable duration that were recruited from outpatient clinic of Banha university in the period between August 2014 and April 2016.
Participants: The study included two groups each group composed of 25 eyes.
Group (I): 25 eyes underwent surgical removal of the pterygium with limbal conjunctival auto graft procedure.
Group (II): 25 eyes underwent surgical removal of the pterygium with single subconjunctival Bevacizumab injection.
Evaluation: Patients were evaluated by photo slit lamp and slit lamp examination on the 1st post-operative day, one week, two weeks, one month then every 3 months for at least one year. Visual acuity, refraction, and IOP were measured in each visit. Evaluation is for the occurrence of any complication or recurrence.
Results: Fifty eyes (25 males, 25 females) were included in the study. mean age: 48.94±11.21 years. Preoperative symptoms ranged from 1 to 3 years. In all eyes, pterygium was located nasally. The size of pre-operative corneal invasion Mean ±SD was in group I (3.63±0.54 mm) and in group II (3.43±0.23 mm). There were no statistically significant differences between both groups in age, size of corneal invasion, dimensions of pterygia
In group I, in which patients had pterygium excision with conjunctiva-limbal autograft,
24 of 25 patients showed no sign of recurrence by the end
of the follow-up period (96%). One patient had signs of grade 1 recurrence.
In group II, in which pterygium excision was associated with subconjunctival injection of bevacizumab at the end of the procedure,
five patients (20%) had signs of recurrence seen by the 1st month postoperatively. One of them developed grade 2 recurrence 3 months later.
Conclusions: TAccording to our results there is no doubt that conjunctival auto graft was a better technique in lowering the primary pterygium recurrence than single dose intra operative bevacizumab injection with no significant difference in intra and post-operative complications. |
