Background: In conservative breast surgery (CBS), the larger the volume of
breast tissue resected the poorer the cosmetic outcome, therefor, introduction
of ultrasonography in the excision of palpable breast cancer aims to minimize
heathy tissue excision and ensure oncologically-safe excision, hence, better
cosmetic outcome than in palpation-guided surgery (PGS).
Aim: A comparison between ultrasound-guided surgery (UGS) for palpable
breast cancer with PGS on safety margin, re-excision rate and cosmetic
outcome.
Methods/design: This is a prospective randomized controlled study
conducted on 79 female patients with palpable early breast cancer. Patients
were randomized to underwent either UGS or PGS. Mean distance between
the tumor and the resection margin, re-excision rate, operative time, cosmetic
outcome and patient satisfaction were assessed.
Statistical analysis used: Data management and statistical analysis
were done using SPSS version 28 (IBM, Armonk, New York, United States).
Quantitative data were assessed for normality using the Shapiro-Wilk test and
direct data visualization methods. According to normality, quantitative data
were summarized as means and standard deviations. Categorical data were
summarized as numbers and percentages. Quantitative data were compared
between the studied groups using independent t-test. Categorical data were
compared using the Chi-square test. Multivariate logistic regression analysis
was done to predict good to excellent patient satisfaction. All statistical tests
were two-sided. P values less than 0.05 were considered significant. |
