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Prof. Alaa El-Sayed Ahmed Ahmed Amin :: Publications: |
Title: | Modified spectrophotometric method for the determination of some important antibiotics through charge-transfer complexatioin reaction with chloranil. |
Authors: | Alaa S. Amin, |
Year: | 1996 |
Keywords: | Not Available |
Journal: | Not Available |
Volume: | Not Available |
Issue: | Not Available |
Pages: | Not Available |
Publisher: | Not Available |
Local/International: | International |
Paper Link: | Not Available |
Full paper | Alaa El-Sayed Ahmed Ahmed Amin_37.pdf |
Supplementary materials | Not Available |
Abstract: |
A new modified Spectrophotometric procedures are presented for the determination of three pharmaceutical antibiotic compounds through charge-transfere complexation reaction with chloranil. The complex shows an absorption mAxima at 550 nm, having a molar absorptivity coefficient of 5.55×10,7.81×10 and 1.38×10 1. molcm for ampicillin, amoxycillin and neomycin, respectively. Optimization of the reaction conditions has been investigated Obediance to Beer's law (40μg/ml) permitted the assay of thes drugs in its dosage forms A variety of pharmaceutical dosage forms containing ampicillin, amoxycillin and neomycin are successfully analysed by the proposed procedure. |