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Assist. Alaa Mohamed Behairy Mohamed :: Publications: |
Title: | Liquorice (Glycyrrhiza glabra) hydroethanolic extracts effectively alleviate Thioacetamide -induced hepatotoxicity and hematoxicity in experimental rats through their antioxidant nature |
Authors: | Alaa Behairy; Ashraf Elkomy;Faten Elsayed |
Year: | 2020 |
Keywords: | Hematotoxicity;Hepatotoxicity;Liquorice Extract;Rats;Thioacetamide. |
Journal: | International Journal of Pharmacology and Toxicology (IJPT) |
Volume: | 9 |
Issue: | (1)(2021) |
Pages: | 10-16 |
Publisher: | Alaa Behairy |
Local/International: | International |
Paper Link: | |
Full paper | Alaa Mohamed Behairy Mohamed_IJPT-31244.pdf |
Supplementary materials | Not Available |
Abstract: |
Background: Liquorice (Glycyrrhiza glabra) is a high valued plant and used in a lot of countries around the world. The liquorice (LQ) has a remarkable medicinal, nutritional and socio-economic value. Therefore this study was designed to clarify the protective effect of liquorice hydroethanolic extract against Thioacetamide (TAA) induced hepatotoxicity and hematotoxicity in rats. Materials and Methods: Seventy white Albino male rats were used in this study and after acclimatization rats were subjected to different treatments blood and tissue samples were collected after day 30 post administration, biochemical, antioxidant, hematological and histopathological examinations were utilized to investigate hepatoprotective activity of liquorice hydroethanolic extract. Results: TAA significant (P |