The lack of vaccines and drugs for viruses becomes a big challenge in the recent years,
especially with the big variety of families and serotypes for each virus, and this problem
appear clearly with RNA viruses; because the big mutation and instability nature of this
type of viruses, which prevent from the long life affect of the vaccines, for that reason a
lot of researches have been conducted to overcome this problem whether at life cycle,
genome sequencing, second and tertiary structure level. one of the viruses which affects
directly on the animal health and its life at all, and also affects on the economics of the
world is foot-and-mouth disease virus (FMDV) which is belonging to picornafamily. The
objective of this paper is : introduce a data base for FMDV to help researchers in this
point of research. The proposed data base consisting of four level of data: Complete
genome, Internal ribosome entry site (IRES), Domain 3 of IRES, and Apical region of
domain 3 with total number of records around 2000 records at the different levels of data
. The data base named CIDA (the first letter of each level of data) and can accessed and
downloaded free at : www.claes.sci.eg/fmdv.CIDA. The data are available in FASTA
format. |
