Non-melanoma skin cancer is an important disease. It is the most
common cancer world-wide and its incidence all over the world is rapidly
increasing in alarming manner. It has a high cure rate, but neglect can
allow the cancer to enlarge, causing possible disfigurement and disability.
Non-melanoma skin cancer can be prevented through public
awareness of their possible risk for NMSC development and how to avoid
this.
World-wide efforts have been made to determine the possible
etiological factors of NMSC and to find clues for its development,
implyingthis informationin the prevention of the disease.
The present study aimed at determining the incidence of NMSC in
a one year period in patients attending the Dermatology Outpatient Clinic
in Benha University Hospital and to clarify some of the epidemiological
features of these tumors. The study is concerned with environmental
influences, predisposing host conditions, clinical features and
histopathologicalpatterns ofNMSC in these patients.
Thirty seven patients were collected in one year period from
Jaurnary 2002 to January 2003 and subjected to full history taking,
clinical examinationand histopathological examination of lesions.
The incidence of NMSC estimated was 0.19% and although this
incidence is not an accurate incidence, yet it is of a considerable
importance.
Most of patients were above the age of forty. Males and females
were nearly equally affected. Patient's occupations varied, however most
of them work in cultivating lands exposing themselves to the hazards of
Summary and Conclusion •••• !!I!I!II!!!!!!!!!!!!!!!l!!l!!!!!!!!!!!!!!l!!l!!!!llB!!!!!II!!!!!!!l!!l_ ••• !!!!!!!!!!!!!!!!I_l 70
the sun and to inorganic arsenic compounds used in pesticides and
insecticides. In the present study, most of patients had a naturally brown
skin, dark brown to black hair and brown eyes. This suggests that there is
increased risk among persons with relatively pigmented skin than what
was expected.
Basal cell carcinoma was more common than see with a ratio
1.46: 1. All Bee lesions developed on a normal skin, while 50010 of see
lesions originated from a precancerous lesion. Seventy percent of lesions
were on the face.
The most common Bee type found was the nodulo-ulcerative
type. It showed a positive correlation with female sex of patients, finding
the lesion on mid upper face and being of the solid histopathological
variety.
Although, see has multiple appearances and stages, only one
lesion, however, was metastasizing to regional lymph nodes. They were
mostly of the well-differentiated histopathological type and of grade I or
II.
These findings provide insights to the epidemiological features of
NMSe in our country. A cooperative work of primary health care
clinics, governmental hospitals, university hospitals and private clinics
allover Egypt to find out the real incidence of NMse in Egypt is
needed. Also public awareness of the dangers of solar radiation and the
necessary preventive measures are required |