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Dr. Ali Abd Alnaby Ali Morssy :: Publications:

Title:
Prevention of postpartum Hemorrhage with Sublingual Misoprostol or Oxytocin
Authors: M.R.Gohar, A.A.Eldeen, A.A.Morsy and P.A.Eldamer
Year: 2019
Keywords: Keywords: Misoprostol, Oxytocin, Postpartum hemorrhage
Journal: Benha Journal of Applied Sciences (BJAS) print : ISSN 2356–9751 Vol.(5) Issue(1) part (2) (2020), (233-238)
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: Local
Paper Link: Not Available
Full paper Ali Abd Alnaby Ali Morssy_3.pdf
Supplementary materials Not Available
Abstract:

Abstract Postpartum hemorrhage is a life threatening situation and one of the important causes of maternal mortality and morbidity, worldwide. To evaluate the effectiveness of a low dose (400ug) of misoprostol administrated sublingually compared to 10 IU of intramascular oxytocin for the reduction of postpartum blood loss. A total of 120 patients were randomized to receive either 400µg misoprostol sublingually or 10 IU oxytocin intramuscularly after vaginal delivery. Primary outcome measured was mean blood loss and incidence of primary postpartum hemorrhage (PPH). Secondary outcome measured included change in pre and 24 hour post-delivery hemoglobin and hematocrit values, side effects of the used drugs, and the need for blood transfusion. Results: Although not statistically significant, mean blood loss mean in misoprostol group (301.92 ±132.95) was lower than in oxytocin group (317.58 ±120.12). Incidence of postpartum hemorrhage was (1.7%) in misoprostol group versus in oxytocin group (3.3%). We observed that 6.7% and 8.3% of women experienced a hemoglobin decline of >10% 24 hours after receiving misoprostol and oxytocin, respectively (p = 1.0), the mean of HCT drop in misoprostol group (3.43 ±2.8) and (3.38 ± 2.92) in oxytocin group ( p = 0.92) . Side effects were significantly greater in the misoprostol

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