Background: In adults, eighty-five percent of tumors in the cerebellopontine angle are vestibular schwannomas (VS), which can lead to hearing loss, balance issues, and tinnitus. Advances in diagnostic and surgical techniques have reduced their recurrence rates to less than 1%. However, optimal management remains a challenge, requiring tailored approaches based on tumor characteristics and patient factors. This research aimed to assess the factors influencing management decisions for unilateral vestibular schwannoma, including tumor size, location, patient age, and hearing condition. Methods: This prospective trail involved 30 individuals with unilateral VS treated at Benha University Hospital and International Medical Center. Patients underwent observation, Gamma Knife radiosurgery (GKRS), microsurgery, or a combination approach, with a minimum follow-up of 6 months. Results: The average age of participants was 41 years, with 73.3% undergoing surgical treatment and 70% receiving GKRS. Among GKRS patients, 47.6% received it preoperatively, and 52.4% postoperatively. Tumor progression led to a shift from conservative to active treatment in 72.7% of cases. Postoperative complications included facial nerve palsy (14.3%), edema (9.5%), and cerebrospinal fluid leaks (4.5%). Tumor regrowth was observed in 14.3% of patients treated with GKRS. Conclusion: Management of unilateral VS is influenced by tumor size, location, and patient-specific factors. While conservative management can be effective, progression often necessitates GKRS or surgical intervention. A tailored approach based on these factors optimizes outcomes for patients. |