BACKGROUND: Post-operative atrial fibrillation {AF} after coronary artery bypass graft surgery {CABG} is a frequent complication responsible for high morbidity, a prolonged hospital stay and significant extra-costs. Prevention with prophylactic drug therapy has had limited success, therefore alternative approaches are required.
OBJECTIVE: The purpose of our randomized controlled study was to evaluate the efficacy and safety of atrial pacing in the prevention of post-CABG atrial fibrillation by using on-demand atrial pacing via epicardial electrode wire.
PA TIENTS AND METHODS: Sixty patients who scheduled for CABG surgery for severe symptomatic CAD were studied prospectively and randomized to no atrial pacing {30 patients. Control group) versus demand atrial pacing at 90 beats per minute {30 patients, paced group), started immediately after operation and continued for 3days. Their ages ranged 40-74 years {mean age 55 ± 6.2 years). The major end point of the study was the development of AF that lasted? one hour duration or required urgent cardioversion.
RESULTS: The overall incidence of A.F among the studied population was 26.75% { l6patients} during the study period. It was significantly lower in paced group versus non paced group (13.3% VS 40%, p |
