In the present study, organic and inorganic nanosilica were evaluated
against the terrestrial snail Eobania vermiculata including mortality
percentage, some life-cycle aspects studied included, also their effects on
change in some biochemical parameters in albino Wistar rats under
laboratory conditions.LC50 values for organic and inorganic nanosilica
treatments on the snail were 303.92µg/ml and 6.282×104 µg/g after five and
three days of treatment respectively. Data showed significant results
against E. vermiculata life- cycle aspects and new generation where
treatments caused a reduction of copulation, oviposition and larva stage
percentages reached {(50 and 25), (70.92 and 81.21) and (92.37 and 95.69)
%} for organic and inorganic nanosilica respectively. On rats, there were
highly significant changes in hematological parameters in rats, as there
were a very high significant decreased in WBCs, 4.70 and 4.87 (103/µl)
when treated with organic and inorganic nanosilica respectively, compared
with 10.80 (103/µl) in the control, a very high significant decreased in MCV
by 73.63 and 74.0 (fl) respectively, compared with 91.30 (fl) in the control,
a significant increase in RBCs treated with organic nano silica by 7.30
(106/µl) and a very high significant increase reached 7.90 (106/µl) in treated
with inorganic nanosilica compared with 6.77 (106/µl) in the control. Also,
a very high significance was detected in PLT treated with organic
nanosilica reached 832.0 (103/µl) and a highly significant increase in
treated with inorganic nanosilica by 811.07 (103/µl) compared with 478.0 (103/µl) in the control. |
