Background Patients' safety is fundamental to the provision of health care in all settings. However, avoidable adverse events, errors and risks associated with health care remain major challenges for patient safety globally. They contribute significantly to the burden of harm due to unsafe care. Aim: This study aims to evaluate the effect of implementing nursing care protocol on critical patients' safety outcomes. Design: A quasi experimental - design was utilized to achieve the aim of this study. Setting: The study was conducted in the general intensive care unit at Benha University Hospital. Subjects: Convenience sample of all available nurses (36 nurses) who are working in ICU & A purposive sample of 36 consecutive eligible patients who attended to ICU within 3 months. Result: revealed that, the post mean knowledge and practice scores of nurses regard patients' safety that were exposed to nursing care protocol were higher than their pretest knowledge mean scores, as regard to patients' safety outcomes found that improved post the nursing care protocol than pre protocol, there were positive correlations between total nurses‟ knowledge and practice and laboratory investigation, general signs and symptoms of infection, local signs and symptoms of infection, physiological parameters measurement on admission and after one week. Conclusion: the total mean score of nurses‟ knowledge was improved after implementation of nursing care protocol than pre implementation, The total mean score of nurses‟ practice was improved after implementation of nursing care protocol than pre implementation with highly statistically significant differences among all items pre and post nursing care protocol implementation & there was an improvement in patient‟ safety outcomes for study group than control group after one week with statistically significance difference. Recommendation: The study recommended that; In service education should provide in hospital to improve nurses‟ performance regarding patient safety measures through acquiring knowledge and through implementing the established standards of care which must be updated periodically. |