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Prof. Amel Mohammed Ahmed El Asely :: Publications:

Title:
Modulation of genotoxicity and endocrine disruptive effects of malathion by dietary honeybee pollen and propolis in Nile tilapia(Oreochromis niloticus)
Authors: Mohamed M.M. Kandiela,*, Amel M. El-Aselyb, Hasnaa A. Radwan c,Amany A.Abbassb
Year: 2014
Keywords: tilapia, genotoxicity, modulation, malathion, bee pollen, problis
Journal: Cairo University Journal of Advanced Research
Volume: 5
Issue: 6
Pages: 671-684
Publisher: hosted by El Savier
Local/International: International
Paper Link:
Full paper Not Available
Supplementary materials Not Available
Abstract:

The present study aimed at verifying the usefulness of dietary 2.5% bee-pollen (BP) or propolis (PROP) to overcome the genotoxic and endocrine disruptive effects of malathion polluted water in Oreochromis niloticus (O. niloticus). The acute toxicity test was conducted in O. niloticus in various concentrations (0–8 ppm); mortality rate was assessed daily for 96 h. The 96 h-LC was 5 ppm and therefore 1/5 of the median lethal concentration (1 ppm) was used for chronic toxicity assessment. In experiment (1), fish (n =8/group) were kept on a diet (BP/PROP or without additive (control)) and exposed daily to malathion in water at concentration of 5 ppm for 96 h (acute toxicity experiment). Protective efficiency against the malathion was verified through chromosomal aberrations (CA), micronucleus (MN) and DNA-fragmentation assessment. Survival rate in control, BP and PROP groups was 37.5%, 50.0% and 100.0%, respectively. Fish in BP and PROP groups showed a significant (P

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