Abstract
Objectives: To detect average dimensions and indices of normal brain cerebral hemispheres and lateral ventricles in relation to age and gender.
Subjects & Methods:
135 subjects; 70 males (M) and 65 females (F)were categorized into 4 age groups (G): GM1 & GF1 included subjects60 years old. CT imaging was conducted according to Agapejev; using high resolution scanner for measuring the width of right (RAH) and left anterior horns (LAH) of lateral ventricle, the bifrontal distance (ff) and inner skull width (FF) at this level, the bifrontal index (ff//FF), the bicaudate distance (cc), and inner skull width (CC) at this level and the bicaudate index (cc/CC).
Results:
Bifrontal distance was significantly wider in GM4 than GM3 and in GM2 and GM4 than GF2 and GF4. The FF distance increased progressively but non-significantly among groups G1-3 in both sexes, but non-significantly decreased in G4 compared to G3 in both sexes.The FF distance was significantly wider in GM1-3 compared to GF1-3. Bifrontal index showed non-significant difference between all GF groups. It showed non-significant difference between GM1-3 groups, but was significantly higher in GM4 than GM3. Bicaudate distance of GM4 was significantly wider than GM3, in GF3 than GF2, GF4 than GF3 and in GM1 and GM4 compared to GF1 and GF4, respectively. The CC distance showed non-significant increase in GM2 than GM1, but showed non-significant decrease in GM3 than GM2 and in GM4 than GM3. The CC distance showed non-significant increase in GF2 than GF1 and in GF3 than GF2, but was non-significantly decreased in GF4 than in GF3. The CC distance was significantly larger in males compared to females in G1-3 groups, but non-significantly in G4. Bicaudate index showed non-significant difference up GM3 but was significantly higher in GM4 compared to GM3. Bicuadate index showed significant difference between GF3, GF2 and GF4, GF3 groups. Width of RAH was significantly wider in GM4 compared to GM3 and in GM4 than GF4. Width of LAH was significantly wider in GM4 than GM3, GF2 than GF1 and in GF3 than GF2. LAH width was significantly wider in GM1, GM2 and GM4 compared to females.
Conclusion:
Cerebral and lateral ventricle dimensions showed steady increase with age and being larger in males than in females. Subjects older than 60 years showed significant reduction of bifrontal and bicaudate indices with evident difference according to gender.
Keywords:
Cerebral hemispheres, Lateral Ventricle, Dimensions, Indices, Normal subjects, Age, Gender
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