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Prof. Amal Fathy Soliman Mostafa :: Publications: |
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| Title: | Significance of Anti-C1q Antibodies in Patients with Systemic Lupus Erythematosus as A Marker of Disease Activity and Lupus Nephritis |
| Authors: | 1Amal F Soliman, 1Sami EL-Said Egailla, 2Eman R Abdel Gawad, 2Amira I Mansour,3Tohamy H ElKhouly,1Marwa YA Mahgoub |
| Year: | 2016 |
| Keywords: | Anti-C1q Antibodies Systemic Lupus Erythematosus Disease Activity Lupus Nephritis |
| Journal: | THE EGYPTIAN JOURNAL OF IMMUNOLOGY |
| Volume: | 23 |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Amal Fathy Soliman Mostafa_Pages from Anti C1q.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Anti-C1q autoantibodies have been proposed as a useful marker in SLE. This study aimed at measuring serum levels of anti-C1q antibodies in patients with SLE and investigates correlations of this level with the histopathological classes of renal biopsies and disease activity. The anti-C1q antibody level was measured in 30 females SLE patients and 20 controls. The activity of SLE disease was calculated according to the SLE disease activity index. A renal biopsy from patients with clinical manifestations of renal disease was obtained. There was a significant increase in the level of anti-C1q antibodies in SLE patients than controls and in patients with active LN than inactive LN (P |
