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Dr. Amira Ibrahim Mansour Ahmed :: Publications: |
Title: | Significance of Anti-C1q Antibodies in Patients with
Systemic Lupus Erythematosus as A Marker of
Disease Activity and Lupus Nephritis
|
Authors: | Amal F Soliman, Sami EL-Said Egailla, Eman R Abdel Gawad,Amira I Mansour, Tohamy H ElKhouly, Marwa YA Mahgoub |
Year: | 2016 |
Keywords: | Antic1q, Nephritis, SLE |
Journal: | THE EGYPTIAN JOURNAL OF IMMUNOLOGY |
Volume: | Vol. 23 |
Issue: | (1) |
Pages: | 107-116 |
Publisher: | Not Available |
Local/International: | International |
Paper Link: | Not Available |
Full paper | Amira Ibrahim Mansour Ahmed_12-Amira manssour.pdf |
Supplementary materials | Not Available |
Abstract: |
Anti-C1q autoantibodies have been proposed as a useful marker in SLE. This study aimed at measuring serum levels of anti-C1q antibodies in patients with SLE and investigates correlations of this level with the histopathological classes of renal biopsies and disease activity. The anti-C1q antibody level was measured in 30 females SLE patients and 20 controls. The activity of SLE disease was calculated according to the SLE disease activity index. A renal biopsy from patients with clinical manifestations of renal disease was obtained. There was a significant increase in the level of anti-C1q antibodies in SLE patients than controls and in patients with active LN than inactive LN (P |