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Dr. Amira Ibrahim Mansour Ahmed :: Publications:

Title:
Significance of Anti-C1q Antibodies in Patients with Systemic Lupus Erythematosus as A Marker of Disease Activity and Lupus Nephritis
Authors: Amal F Soliman, Sami EL-Said Egailla, Eman R Abdel Gawad,Amira I Mansour, Tohamy H ElKhouly, Marwa YA Mahgoub
Year: 2016
Keywords: Antic1q, Nephritis, SLE
Journal: THE EGYPTIAN JOURNAL OF IMMUNOLOGY
Volume: Vol. 23
Issue: (1)
Pages: 107-116
Publisher: Not Available
Local/International: International
Paper Link: Not Available
Full paper Amira Ibrahim Mansour Ahmed_12-Amira manssour.pdf
Supplementary materials Not Available
Abstract:

Anti-C1q autoantibodies have been proposed as a useful marker in SLE. This study aimed at measuring serum levels of anti-C1q antibodies in patients with SLE and investigates correlations of this level with the histopathological classes of renal biopsies and disease activity. The anti-C1q antibody level was measured in 30 females SLE patients and 20 controls. The activity of SLE disease was calculated according to the SLE disease activity index. A renal biopsy from patients with clinical manifestations of renal disease was obtained. There was a significant increase in the level of anti-C1q antibodies in SLE patients than controls and in patients with active LN than inactive LN (P

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