Background Asthma is a heterogeneous disease, usually
characterized by chronic airway inflammation.
Aim This study was carried out to evaluate the level of vitamin
D and immunoglobulin E (IgE) in asthmatic patients during
exacerbation and after remission.
Patients and methods This study was carried out on 30
patients with bronchial asthma diagnosed and classified
according to Global Initiative for Asthma 2015 and 20 healthy
individuals. Serum vitamin D and IgE were measured using
enzyme-linked immunosorbent assay for all participants.
Results Vitamin D level was highly significantly lower in the
asthmatic group during exacerbation compared with the
asthmatic group after remission and the control group, and
the total IgE level was highly significantly higher in the
asthmatic groups compared with the control group.Conclusion Asthmatic patients might have an increased risk
of having vitamin D deficiency during exacerbation and after
remission, whereas the levels of serum total IgE level was
high in asthmatic patients compared with normal individuals. |
