Objectives: To test the technical feasi-bility and clinical utility of prostatic artery embolization (PAE) in high risk patients with benign prostatic obstruc-tion (BPO).
Patients and methods: Twenty-six pa-tients with LUTS due to BPH were subjected to PAE between June 2014 and March 2016, in a prospective study. All patients underwent assess-ment of IPSS, QoL, Qmax, PVR urine volume, prostate volume, serum PSA, pre-procedure and multiple measure-ments at 1, 3, 6, and 12 months after PAE.
Results: The procedure was technical-ly successful in 24/26 patients (92.3%) and failed in two (7.7%). Bilateral PAE in 20(76.9%) cases and in 4(15.4%) unilateral PAE were accom-plished. At last follow-up visit, a de-crease by 23.5% in PV and 28.5% in PSA level. The IPSS decreased by 17.9 points, the QoL score decreased by 2.3 points. The Qmax increased by 63.1%. Clinical improvement was better after bilateral PAE than unilateral proce-dure. Complications were recorded in 3(11%); AUR in 2(8%) and hemo spermia in 1(4%). Post embolization syndrome occurred in three (11%). All remaining patients were improved at the time of last follow-up, stopped all prostatic medication.
Conclusion: PAE is an effective treat-ment in patients with LUTS due to BPH who are at high risk or not can-didates for surgery. The Procedure seems to be effective regardless of prostate size and is associated with early convalescence and short hospital stay. However, the advantages of PAE must be weighed against the risk of technical and clinical failures.
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