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Dr. Ansaam Abdul Salam Ahmadi :: Publications: |
Title: | اDiffering functional mechanisms underlie cognitive control deficits in psychotic spectrum disorders |
Authors: | Ansam Elshaikh |
Year: | 2020 |
Keywords: | Not Available |
Journal: | psychiatry neuroscience |
Volume: | 45 |
Issue: | 6 |
Pages: | Not Available |
Publisher: | Not Available |
Local/International: | International |
Paper Link: | |
Full paper | Ansaam Abdul Salam Ahmadi_ELshaikh2020.pdf |
Supplementary materials | Not Available |
Abstract: |
Functional underpinnings of cognitive control deficits in unbiased samples (i.e., all comers) of patients with psychotic spectrum disorders (PSD) remain actively debated. While many studies suggest hypofrontality in the lateral prefrontal cortex (PFC) and greater deficits during proactive relative to reactive control, few have examined the full hemodynamic response. Methods: Patients with PSD (n = 154) and healthy controls (n = 65) performed the AX continuous performance task (AX-CPT) during rapid (460 ms) functional neuroimaging and underwent full clinical characterization. |