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Prof. Ashraf Talaat Mahmoud Abd El Samad :: Publications: |
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| Title: | High Plasma Retinol-Binding Protein-4 Level is Associated with Impaired Glucose Metabolism in Obese Subjects. |
| Authors: | Mohamed Awad,Ashraf Talaat, El said el nahal, Mohamed Fawzy |
| Year: | 2013 |
| Keywords: | Adipokines, RBP4, Insulin resistance, HOMA-IR, HOMA-B and Type 2 DM. |
| Journal: | British Journal of Science |
| Volume: | 9 |
| Issue: | 2047-3745 |
| Pages: | 51 - 66 |
| Publisher: | British Journal of Science |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Ashraf Talaat Mahmoud Abd El Samad_British Journal of Science 51.docx |
| Supplementary materials | Not Available |
| Abstract: |
Background:Retinol-binding protein 4 (RBP4) is a novel adipokine that induces insulin resistance in mice.Objective: Measurement of serum RBP4 concentration and relationship to insulin sensitivity and secretion in obese subjects with dysglycemia.Design and Participants: This case-control study consisted of 100 subjects, 20 of them were healthy lean subjects and 80 obese patients .They were divided into three groups : normal glucose tolerance (NGT; n = 20), impaired glucose tolerance (IGT; n = 20), and type 2 diabetes (n = 40). Laboratory and anthropometric measurements including, serum RBP4 levels, were assessed.RESULTS: Plasma RBP4 levels were higher in obese IGT and T2DM subjects compared with obese NGT subjects (23.7+10, 26.3+10 vs. 16.64+8 +g/ml, P |
