| You are in:Home/Publications/Anti-Nucleosome Antibodies in Systemic Lupus Erythematosus as a Diagnostic Tool and Useful Marker for Lupus Nephropathy | |
Prof. Ashraf Talaat Mahmoud Abd El Samad :: Publications: |
|
| Title: | Anti-Nucleosome Antibodies in Systemic Lupus Erythematosus as
a Diagnostic Tool and Useful Marker for Lupus Nephropathy
|
| Authors: | Yasser Abdel-Hamid, Ashraf Talaat, Khalid Bilal, Azza Abdul Aziz Abdul Hamid, Youssef El-Bayoumi |
| Year: | 2008 |
| Keywords: | --- |
| Journal: | - Egypt Rheumatology & Rehabilitation |
| Volume: | V. 34 No. 4 |
| Issue: | --- |
| Pages: | 579 - 595 |
| Publisher: | - Egypt Rheumatology & Rehabilitation |
| Local/International: | Local |
| Paper Link: | Not Available |
| Full paper | Ashraf Talaat Mahmoud Abd El Samad_Doc6.docx |
| Supplementary materials | Not Available |
| Abstract: |
Objective: To investigate the clinical utility of anti-nucleosome antibodies (anti-NCS) for the diagnosis of SLE and as a marker of disease activity. Also, to explore their role in biopsy-proven lupus nephritis. Methodology: The study was conducted on 83 SLE patients diagnosed according to the revised ACR criteria. Serum IgG anti-NCS antibodies were detected with ELISA for the patients and 100 matched apparently healthy subjects as, a control group. Renal biopsies were performed for 44 patients with renal involvement and classified according to the WHO classification criteria. Results: Serum anti-NCS antibodies levels were significantly higher in patients with renal affection, arthritis (p |
