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Prof. Ayman Mahmoud Abdel Mofeed Hassan :: Publications: |
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| Title: | Treatment of Acute Iliofemoral Deep Vein Thrombosis; Does Catheter Directed
Thrombolytic Therapy Change Outcomes? |
| Authors: | Ayman M. Fakhry1, El-Sayed A. Abd El-Mabood2,3, Waleed A. Sorour4, Ayman M. Abdelmofeed2, Taher H. Elwan2,5,Ahmed Fouad Ahmed2 Mohamed E. Abd Ellatief 2 and Saied ELMOKKADEM |
| Year: | 2019 |
| Keywords: | Iliofemoral venous thrombosis, Catheter-directed thrombolysis; Standard anticoagulation, Post-thrombotic Syndrome |
| Journal: | Cardio Open, 2019 |
| Volume: | Volume 4 | Issue 3 | 1 of 11 |
| Issue: | Volume 4 | Issue 3 | 1 of 11 |
| Pages: | Volume 4 | Issue 3 | 1 of 11 |
| Publisher: | www.opastonline.com |
| Local/International: | International |
| Paper Link: | |
| Full paper | Ayman Mahmoud Abdel Mofeed Hassan_treatment-of-acute-iliofemoral-deep-vein-thrombosis-does-catheter-directed-thrombolytic-therapy-change-outcomes-coa-19.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Background: Iliofemoral deep vein thrombosis (DVT) is associated with severe post-thrombotic morbidity when treated with anticoagulation alone. Catheter- directed thrombolysis (CDT) allows early removal of thrombus and reduces valvular reflux and Post-thrombotic Syndrome (PTS). Patients and methods: This prospective randomized multi-center controlled two- arm blind study was conducted in 6 centers on 252 patients with iliofemoral DVT. Patients were randomly allocated by using simple random allocation cards method into two groups; Group (A): CDT followed by oral anticoagulation (N=126 (50%)), Group (B): Standard DVT therapy (N=126 (50%)). Follow-up was for 24 months. Results: Patients of group (A) significantly complained less pain at 10 & 30 days (P-Value: 0.02 & 0.04 respectively). Also there was significant decrease in leg circumference in group (A) at 10 & 30 days (P-Value: 0.001 & 0.03 respectively). Patency of iliac vein segment was significantly higher in group (A) during the 24 months follow up (P-Value |
