Macleaya cordata (M. cordata) is a herbal plant that has abundant amounts of
sanguinarine, which has many biomedical properties. The effects of M. cordata dietary
supplementation on the productive performance, some blood constituents, and growth-
related genes’ expression were evaluated in turkey. M. cordata extract was dietary
supplemented to turkey at levels of 25, 50, and 100 ppm and a control group. Growth
performance measurements (FBW, ADG, and FCR) and production efficiency factor for
turkey (BPEF) were similar (p > 0.05) in all supplemented groups. M. cordata has no
adverse effects (p > 0.05) on the birds’ health regarding hematological (Hb, RBCs,
WBCs, and PCV) and blood biochemical indices evaluating liver function, kidney function,
and lipid profile. Moreover, the mRNA expression of growth-related genes, such as
growth hormone receptor (GHR), insulin-like growth factor 1 (IGF-1), cyclooxygenase
3 (COX-3), adenine nucleotide translocase (ANT), and uncoupling protein 3 (UCP-3)
were upregulated (p < 0.001) in M. cordata treatments with the highest value for SG50
compared with the control group. We concluded that exogenous M. cordata dietary
supplementation upregulated the expression of growth-related genes in turkey at a level
of 50 ppm without adverse effects on their health status regarding hematological and
biochemical indices. |
