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Dr. dania mohamed :: Publications: |
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| Title: | Hepatorenal Protective Effect of Dandelion (Taraxacum officinale L.) and Its Role in Improving Exercise Capacity in Type 2 Diabetic Albino Rats: Possible Underlying Mechanisms |
| Authors: | Walid Mostafa Said Ahmed 1, Amir Soliman 2, SafyEldin Mahmoud AboAli3, Elsayed A. Eid 4, Rehab Mohamed El shahat5, Amer M.Abdel hamid6, Dania Abdelhady Mohammed7, Omnia Saeed Mahmoud Ahmed8, Asmaa M. Al-Emrany9 |
| Year: | 2022 |
| Keywords: | Not Available |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | Local |
| Paper Link: | Not Available |
| Full paper | dania mohamed_20230428112659pmNQ22954 .pdf |
| Supplementary materials | Not Available |
| Abstract: |
Background: The tremendous rise in the economic burden of type 2 diabetes (T2D) has prompted a search for alternative and less expensive medicines. Dandelion offers a compelling profile of bioactive components with potential hepato-renal and anti-diabetic properties. In many countries, it is used as food and in some countries as therapeutics for the control and treatment of T2D. Objective: To investigate hepatorenal protective effect of dandelion and its role in improving exercise capacity in type 2 diabetic albino rats and its possible underlying mechanisms. Materials and methods: Induction of partial diabetes in 30 rats by STZ followed by biochemical investigation of C- peptide and blood glucose level with several kidney and liver parameters. In addition to non-enzymatic and enzymatic anti-oxidants in vitro were evaluated. Also, the pro-inflammatory mediators and the expression levels of pro-oxidants/pro-inflammatory and anti-inflammatory mediators using qPCR. |
