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Dr. dania mohamed :: Publications:

Title:
Bee venom ameliorates gentamicin-induced kidney injury by restoring renal aquaporins and enhancing antioxidant and anti-inflammatory activities in rats
Authors: Naglaa Mokhtar13,14, Moaz A. Mojaddidi15, Madaniah O. Zakari15, Samah F. Ibrahim1, Dania Abdelhady16,17* and Laila Mostafa2
Year: 2025
Keywords: Not Available
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: Local
Paper Link: Not Available
Full paper dania mohamed_GM-BV Frontiers Pharm 2025.pdf
Supplementary materials Not Available
Abstract:

Introduction: Gentamicin (GM) is a frequently used aminoglycoside for managing serious illnesses; nonetheless, renal complications limit its use. Bee venom (BV) is a biological toxin that exhibits anti-inflammatory and antioxidant activities. This study was designed to explore the mitigating effect of BV remediation on GM induced renal injury. Methods: Twenty male rats were divided into four groups (five rats each), namely, control (saline subcutaneously); BV group (1 mg/kg S/C twice weekly for 1 month); GM group (100 mg/kg i. p. for 1 week); and GM-BV group (the same aforementioned dosages ofGMand BV, withGMadministered in the last week for 4 weeks).

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