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Prof. Evat Isaac :: Publications: |
Title: | Novel synthesis of phthalazine derivatives as antimicrobial agents |
Authors: | Yvette Issac, Eman El-Karim, Shafie Donia, Mohamed Behalow |
Year: | 2002 |
Keywords: | Not Available |
Journal: | Not Available |
Volume: | Not Available |
Issue: | Not Available |
Pages: | Not Available |
Publisher: | Not Available |
Local/International: | International |
Paper Link: | Not Available |
Full paper | Not Available |
Supplementary materials | Not Available |
Abstract: |
Reaction of 4-(phenoxathiin-2-yl)-1-oxy or mercaptophthalazines 2a, c with phthalyl or tosylamino acids 3 and 4 has been found to yield 5, 6a-j. Hydrazinolysis of 5, 6a-e furnished amino derivatives 5, 6k-o. Some of the newly synthesized products were tested for their antimicrobial activities. |