Context: After nasal surgeries,the experience of postoperative packing removal is considered the worst one due to the acute pain they may feel and the discomfort experienced should nasal bleeding occur. Aims:To compare Fibrin glue and Merocel in surgical resection of hypertrophied inferior nasal turbinate in terms of efficiency and patient comfort. Settings and Design: This randomized controlled study was conducted in Helwan Medical University Hospital,Egypt in the period 2014-2015. Methods and Material: Participants were randomly allocated to the study group and the control group. For the study group fibrin sealant was used, and for the control group Merocel was used. The primary outcome was the prevalence of perioperative nasal bleeding and postoperative adhesions. Statistical analysis used: All statistical tests were made using a significance level of 95%. Comparisons between variables were made using t-test, Mann-Whitney test, Chi-square test or Phi-Cramer test. Results: Sixty subjects were included in the analysis, 30 in the Fibrin Glue group and 30 in the Merocel group. The two groups were comparable regarding the baseline characteristics. Perioperative bleedings were experienced in 8(26.6%) of the Fibrin glue group and in 18(60%) of the Merocel group (p-value 0.001). Adhesions were more prevalent in the Merocel group 24(80.0%) than in the Fibrin glue group 16(53.3%), (p-value 0.023). Also, edema was more prevalent in the Merocel group 17(56.7%) than in the Fibrin glue group nine (30.0%), (p-value 0.034). There was a difference (p < 0.05) between Fibrin Glue and Merocel group regarding the pain during packing removal, the pain or pressure effect due to packing, difficulty in swallowing, and general satisfaction. Conclusions: In conclusion, the efficiency and patient comfort are better when using Fibrin glue sealant in inferior turbinectomy when compared to the traditional nasal packing. |
