Background: Intrauterine growth restriction(IUGR) has been defined as the rate of fetal growth that is below normal in
light of the growth potential of a specific infant as per the race and gender of the fetus. A woman with a prior pregnancy
complicated by IUGR has nearly a 20% risk of recurrence. Defects in placental vascular development can cause embryonic
death, can negatively affect fetal growth and can confer a higher risk of disease in the postnatal life.
Objective: study aimed to assess the role of first trimester uterine artery Doppler pulsatility index, placental volume and
placental vascularization assessed in prediction of recurrence of third trimester intrauterine growth restriction.
Methods: In this Prospective longitudinal observational study,two hundred pregnant women with singleton pregnancy from
11 up to 13 weeks with history of intrauterine growth restriction in a previous pregnancy underwent ultrasound assessment
of gestational age, ultrasound assessment of uterine artery pulsatility index, placental volume by 3D ultrasound and placental
vascularization by 3D power Doppler (3DPD).
Results: Placental volume, vascularization index, flow index(F.I), vascularization flow index, and Uterine artery pulsatility
index were significantly lower in IUGR with PET(pre eclampatic toxemia) group and IUGRgroup versus normal group,
(p-value |
