Background: Left ventricular (LV) volumes, ejection fraction (EF) and mass are important prognostic factors in patients with cardiac diseases and are therefore frequently requested for serial testing.
Objective: To assess the effect of LV mass index on systolic and diastolic function in AMI patients.
Patients & methods: This study included 75 patients, selected randomly from those presented to the CCU at Benha University Hospital with AMI. All patients were subjected to full history taking, detection of risk factors as smoking, DM, HTN, obesity and positive family history for early CAD. Twelve leads ECG was done and patients were divided into three group, Group (A): anterior myocardial infarction, Group (B): Non ST elevation infarction, and Group (C): Inferior infarction. Echocardiography was done during CCU admission & one month after discharge to assess LV mass index, LV volume, LV EF%, and diastolic function .Coronary angiography was done to assess the severity of CAD.
Results: We found that LV mass lost, increased ESV & EDV were more in Group B, and Group A , also there was more loss of mass in group that did not receive thrombolytic therapy. The study show low LVMI than the normal value in both group (A) & (B) during the 1st assessment is of prognostic value for development of heart failure after follow up (p<0.05). In the present study the increase in ESV, EDV and mass loss is parallel to decreased systolic function in group A, B, C. The correlation between angiographic score and LVMI was significant in anterior MI group only. Also there was no correlation between LVMI and diastolic function of studied groups.
Conclusion: The reduced LVMI has a significant effect on both systolic and diastolic functions in patients with acute myocardial infarction and can be used as a predictor for development of heart failure.
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