ABSTRACT
The present study was to evaluate anti-leukopenia and antioxidant effects of Moringa peregrina seeds oil at 381mg/kg.in 400mg/kg.b.w. benzene and/or 20mg/kg.b.w.,5-Fluorouracil induced leukopenia rats. 2 weeks after induction of leukopenia in rats, Moringa peregrina seeds oil at 381mg/kg. was administrated for 30 consecutive days. On the 31th day, the rats were sacrificed for the estimation of hemoglobin (Hb%), complete blood cell count Leucocyte (WBC) and platelet count (PLT), as well as biochemical parameters; alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), lipid peroxides (TBARS), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), total cholesterol (TC), triglycerides (TG), HDL-C, LDL-C, p53gene expression, nitric oxide (NO) and tumor necroses factor-α (TNF-α). The results of this study also showed that administration of Moringa peregrina seeds oil at 381mg/kg.b.w. to leukopenia induced rats demonstrated a significant (P |
