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Dr. Howaida Elkholy :: Publications:

Residue of levamisole in broiler breeder chickens edible tissue and eggs
Authors: El-kholy, HM and Kemppainen, B
Year: 2005
Keywords: Not Available
Journal: Journal of Poultry Science
Volume: 84
Issue: 1
Pages: 9-13
Publisher: Oxford University Press
Local/International: Local
Paper Link:
Full paper Howaida Elkholy_lev rsidue.pdf
Supplementary materials Not Available

Levamisoleiscurrentlybeingusedtotreat capillaria infection in chickens even though there is no published withdrawal information available for levamisoleinchickens.Tissueresiduewithdrawaloflevamisole in chickens was studied in 32 healthy broiler breeder chickens at the age of 32 wk (peak of egg production). Levamisole residues in chicken tissues, eggs, and plasma were determined by HPLC with ultraviolet (UV) detection at 225 nm. The highest level of residue and longest withdrawalafteroraladministrationof40mg/kglevamisole to chickens was in the liver. On d 3 the level of levamisolewereundetectableintheplasma.On d 9, levamisole residue in eggs was 0.096µg/g and on d 18 it was 0.06µg/gorlessinalltheanalyzedchickentissues.Those levelswerelowerthan therecommendedmaximumresidue limit (MRL). The withdrawal time for levamisole in chickens was longer than for other species tested, which is due in part to a larger dose of levamisole being recommended for chickens. In conclusion from this research, 9 d are needed for levamisole in eggs to be less than the MRL, and 18 d of withdrawal are needed before medicated birds are slaughtered if their tissues are to be safe for human consumption.

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