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Prof. Ibrahim Sayed Ahmed Zamzam :: Publications:

Title:
Microsopic and volumetric comparative study of the toxic effects of some antioxidants on the deterioration action of thermally oxidized Sunflomer Oil on The Liver of male Adult Albino Rats
Authors: Ibrahim SA Zamzam, t1D
Year: 2004
Keywords: Not Available
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Local/International: International
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Abstract:

Forty adult male albino rats were used in this experiment to evaluate the effects ofsome antioxidants on the deterioration action ofdiet containing thermally oxidized sunflower oil used for frying potatoes at 180±5°C. Antioxidants (dl-a-tocopherol, ronoxan and ascorbyl palmitate) were added to sunflower oil before frying in concentration that increased its oxidative stability by more than two folds. Rats were divided into 5 groups, 8 rats for each, each group housed indiVidually and were fed on experimental diet for 8 weeks. No significant difference in the hepato-index ofrats in different groups. However, there is significant decrease infeed intaRe ofthe rats in different experimental groups in comparison to the control group. Feed effiCiency ratio of the diet containing thermally oxidized frying oil supplemented with 100 ppm tocopherol before frying was not Significantly different than that containing fresh sunflower oil, on the other hand, feed efficiency ratios ofthe diet containing thermally oxidized frying oil supplemented before frying with 100 ppm ascorbyl palmitate or 200 ppm ronoxan were not Significantly different than that containing thermaliy oxidized frying oil without addition. Statistical analysis ofAg NORs in hepatocytes of rats indicated thaI addition ofronoxan or ascorbyl palmitate to sunflower oil before frying had lower Significantly the mutagenic activity of thermally oxidized frying oil. The changes which recognized in the Histological results in the form of hepatic infiltration, congestion and di!a!atic:~ of centra! veins and perta! ...'cssc!s and degeneration

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