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Prof. khaled mohamed sharafeldein :: Publications:

Title:
The protective role of honey against cytotoxicity of cadmium chloride in mice
Authors: Asmaa Shahrour Mohamed Zowail Asmaa Shahrour; Mohamed Zowail; Khaled Sharafeldin
Year: 2016
Keywords: Cadmium, Honey, sperm, chromosome aberrations.
Journal: African Journal of Biotechnology
Volume: 15
Issue: 46
Pages: 2620-2626
Publisher: AcademicJournals
Local/International: International
Paper Link: Not Available
Full paper khaled mohamed sharafeldein_C6E387861701.pdf
Supplementary materials Not Available
Abstract:

The present study aimed to investigate the honey (HY) protective role in opposition to cadmium (Cd) induced chromosomal aberrations of bone marrow and sperm abnormalities. Forty five (45) adult male albino mice were caged into six groups. Mice were injected, i.p, 300 mg HY/kg and/or 0.67 mg CdCl2/kg b.w for 96 h, separately and alternated. The alternated trials were continued for consecutive eight days. Results show that mice injected with cadmium had significant increase in the frequency of aberrant chromosomes as fragment, centric fusion, gap, stickiness and aneuploidy and in sperm abnormality. The administration of HY improved the frequency of the chromosomal aberrations and sperm abnormality induced by Cd.

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