Pelvic adhesion is a major problem that may result from surgical interference . pelvic inflammatory disease or endometrosis and may lead to serious complication as infertility , intestinal obstruction and chronic pelvic pain.
Surgical techniques practiced to minimize peritoneal trauma remain the foundation of adhesions prevention , these include use of magnification , fine caliber microsurgical instrutment, fine suture material meticulous hemostasis , minimizing tissue handling and prevetion of foreign in the operative field
Several trials were performed to prevent postoperative adhesions by using several pharmacological drugs such as corticosteroids , anticoagulant , non steroidal anti- inflammatory drugs, but no drug proved to be universally accepted .
Different barrier agents whether natural or synthetic as omentum , fat, dextran , intercede, were tried but unfortunately none is yet perfect.
The amniotic membrane is characterized by being cheap and available and succeeded in achieving good results in different applications in experimental and clinical studies. This stimulated us to study the efficacy of postoperative adhesions in rabbits .
This study was carried out on 10 rabbits , the right horn was covered with amniotic membrane and the left horn was left as a control . at 2nd look laparotomy adhesions were evaluated and scored according to arora scoring system , biopsies were taken for histopathology.
All results were compared by students test and mannwitney U-test . the mean adhesions score of treated group was unsignificantly higher than of control group . also the mean score of inflammatory cells of treated group was unsignificantly higher than that of control group. |
