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Dr. Mahmoud Hamdy Rizk :: Publications:

Title:
Low Serum Zinc and Spontaneous Bacterial Peritonitis in Patients with HCV-Related Liver Cirrhosis
Authors: Mohamed Abd Ellatif Afifi*1, Heba Esam Abo Foda1, Walid Abd Ellatif Abd Elhalim2, Mahmoud Rizk1
Year: 2026
Keywords: Key words: Cirrhosis, Serum zinc, Spontaneous Bacterial Peritonitis, Ascites.
Journal: The Egyptian Journal of Hospital Medicine
Volume: Vol. 91, Page 5196- 5200
Issue: Vol. 91, Page 5196- 5200
Pages: Vol. 91, Page 5196- 5200
Publisher: National Liver Institute, Menoufiya University (NLI)
Local/International: International
Paper Link:
Full paper Mahmoud Hamdy Rizk_LOW ZINC SPP.pdf
Supplementary materials Not Available
Abstract:

ABSTRACT Background: A serious and common consequence in cirrhotic liver patient is spontaneous bacterial peritonitis (SBP), it means infection of ascitic fluid with unknown operationally treatable etiology in the abdomen. The body contains one of the most prevalent trace elements, zinc (Zn), which is important for growth and development. Objective: To investigate the relationship between low serum Zn levels and SBP development in HCV-related cirrhotic liver patients. Patients and Methods: The study was done on fifty patients with HCV related cirrhotic liver suffering from ascites. Half of them without SBP, classified as group (A), and the other half with SBP on the basis of ascitic fluid polymorphonuclear (PMN) leukocytic count of ≥250 cells/μL in the absence of subsequent peritonitis, no matter the culture results of the ascitic fluid, classified as group (B). Results: The levels of C-reactive protein (CRP), platelet count, and white blood cells (WBCs) were significantly different between the two research groups (P

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