Abstract
Background: Coronary artery disease (CAD) is a worldwide
health concern. Cardiovascular disease (CAD) continues to be
the predominant cause of mortality and morbidity, despite the
enhancement of the current preventive and therapeutic
strategies. This study aimed to correlate between vitamin D
(Vit D), CAD severity and short-term outcome in females versus
males with CAD. Methods: This cross-sectional study was
conducted on 200 cases who were categorized into 2 equal
groups: group A (males) and group B (females). Vit D level was
evaluated in all the cases studied, and they also underwent
electrocardiography, coronary angiography, and calculation of
Syntax. Results: There was a significant negative correlation
between Syntax score and Vit D level, meanwhile there was a
significant positive correlation between Syntax score and
number of affected vessels. Conclusion: There is an association
between Vit D and CAD as it can predict the CAD severity at
cutoff value of ≤ 20 ng/ml, with 98.86% sensitivity, 84.82%
specificity, 83.7% PPV and 99.0% NPV. |