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Dr. marwa kamal mahmoud el sayed :: Publications:

Title:
Predictors of Post Transcatheter Aortic Valve Implantation Electrical Abnormalities and Correlation of Pre Transcatheter Aortic Valve Implantation Computed Tomography with Post Operative Mechanical Trauma Related Complications
Authors: Marwa Kamal Mahmoud 1, Esraa Fathy Elmasry 2*, Safaa Salah Emam 1, Hatem Ibrahim Helal 3, Hany Hassan Ebaid 1
Year: 2025
Keywords: Keywords: TAVI, Aortic Stenosis, Complete AV Block, Calcification, Membranous Septum
Journal: Journal of Rare Cardiovascular Diseases
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: International
Paper Link: Not Available
Full paper marwa kamal mahmoud el sayed_NEMRN557.pdf
Supplementary materials Not Available
Abstract:

Background: Transcatheter Aortic Valve Implantation (TAVI) is a well-established therapy for severe aortic stenosis but is frequently complicated by cardiac conduction disturbances, often necessitating permanent pacemaker implantation (PPM). Pre-procedural Computed Tomography (CT) offers key insights into anatomical risk factors. Objectives: This study aimed to identify predictors of post-TAVI electrical abnormalities (new-onset LBBB and high-grade AV block) and correlate pre-TAVI CT features with post-operative mechanical trauma-related complications. Methods: This prospective cohort study enrolled 60 consecutive adults undergoing TAVI. All patients had pre- and post-procedural ECG and invasive electrophysiology (IEP). CT measurements included Aortic Valve Calcium Scoring (AVCS), membranous septum length, and annular geometry. Primary outcomes were new LBBB and complete AV block (CAVB) requiring PPM. Results: Post-procedure, QRS duration (94.8±9.9ms vs. 99.6±12.9ms, P=0.038) and PR interval (158.6±12.2ms vs. 178.1±15.2ms, P

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