Objectives: To set the efficacy of transrectal Power Color Doppler Ultrasonography
(PCDU), in the prediction of prostate cancer.
Patients & Methods : Sixty patient with possible prostate cancer suspected from an
abnormal digital rectal examination, DRE or elevated prostate surface antigen, PSA,
underwent transrectal ultrasound with Power Color Doppler Ultrasound, PCDU using
a 7 Mhz probe optimized to detect blood flow within the gland and along the capsular
margin. Color flow was graded on a scale, from grade 0 to grade 2, as regards grade 1-
2 were considered positive and grade 0 negative.
Results: Of the sixty patients who underwent histo-pathological confirmation, through
trans-rectal core biopsies, 26 patients had a malignant prostate (43.3%), while 34 cases
had benign histological findings (57%), 8 patients with BPH, 20 cases have chronic
inflammation and 6 cases with focal atrophy.
The sensitivity of PCDU was 92.3%, while the specificity was 64.7%, positive
predictive value was 66.6%, and the negative predictive value was 91.6% for the
diagnosis of prostate cancer.
Conclusion: Focal hyper-vascularity on PCDU was associated with increased like
hood of prostate cancer. This technique appears to increase the sensitivity and to help
identify appropriate sites for biopsy. |
