Background: Sexual dysfunction is a problem that occurs during the sexual response cycle that prevents the individual from experiencing
satisfaction from sexual activity. The assessment of sexual function in women is frequently confounded by many factors, including depressed
mood and other comorbid medical and psychiatric disorders. Sildenafil is selective type 5 phosphodiesterase (PDE5) inhibitors, taken orally
and effective for men with erectile dysfunction. Previous studies suggested that sildenafil may improve the sexual health of women affected by
sexual difficulties such as arousal disorders and may indirectly improve other aspects of sexual life. Sildenafil was effective and well tolerated
in postmenopausal women with sexual arousal disorder without concomitant hypoactive sexual desire disorder or contributory emotional
relationship or historical abuse issues.
Objective: This study aimed to evaluate the effect of sildenafil citrate on female sexual dysfunction.
Subjects and methods: The study was conducted in the Andrology and Gynecology departments of Zagazig and Tanta University Hospitals
during the period from April 2017 to August 2020. Fifty-two married female patients were included in this study. Patients were divided into 2
groups. Group 1 included 26 patients, all received 50mg sildenafil on demand and group 2 included 26 patients who took placebo tablets.
Results: There was no significant difference between the studied groups regarding the demographic data, and FSFI. There was significant
difference between pre and post treatment of sexual dysfunction regarding the Sildenafil arm. There was no significant difference in post
treatment results between the two studied groups as regard sexual dysfunction except in orgasm which showed superior improvement in the
Sildenafil group.
Conclusions: Sildenafil citrate seems to be effective in treating women who could not achieve orgasm. |
