A series of novel metallosurfactants (IIIa-d) was prepared and evaluated as surface active agents.
The synthesis was carried out through two steps: the first was the reaction of fatty acids (Ia-d)
(lauric, palmitic, myristic and steric acid) with morpholine (tetrahydro-1,4-oxazine) to give
morpholin-4-yl-alkan-1-one (IIa-d), respectively. The second step is reaction of product of the first
step (compounds IIa-d) with Fe (III) to give (IIIa-d) metallosurfactants. The chemical structures of
the prepared compounds were elucidated with elemental analysis, FTIR and 1H NMR spectroscopic tools. The surface properties of the prepared metallosurfactants were determined at
different temperature 25, 35, and 45C. The surface tension (c), critical micelle concentration
(CMC), surface tension at CMC (ccmc), effectiveness (pcmc), efficiency (Pc2o), maximum surface
excess (Cmax), and minimum surface area (Amin) were determined. Thermodynamic data including,
free energy, entropy and enthalpy changes (DG, DS, DH) for adsorption at the air–water interface
and also for micellization in the bulk of surfactant solutions were calculated. The antimicrobial
activity of the prepared compounds was determined via the inhibition zone diameter technique
against Gram-positive, Gram-negative bacteria, and some fungal strains as mold and yeast. The
results indicate that the prepared ferrosurfactants have a good surface properties and biological
activities against the tested microorganism. |
