Study design: Prospective observational study. Setting: Banha University centre for reproductive care and a private centre. Objectives: To evaluate the effect of HCG timing for oocyte maturation on the basis of ultrasound measurements made by three dimensional (3D) against those made by conventional two dimensional (2D) ultrasound in relation to the number of mature oocyte collected. Methods: Sixty patients who underwent intracytoplasmic sperm injection (ICSI) in Banha University Reproductive Center and Banha IVF Center were included in this study. Patients over 40 years old , with history of unilateral oophrectomy and ovarian hyperstimulation syndrome were excluded . All patients underwent both 2D and 3D ultrasound examination at same setting . Quality of the 3D image, time needed to perform the ultrasound study, number of follicles, follicular measurements, endometrial thickness and volume were all recorded and compared between both techniques . Data analysis was performed using squared correlation ( R2 ) and Pearson´s correlation tests. Results: 2D and 3D follicular measurements were statistically correlated in (55.1%) of cases. 3D examination showed good quality images in (71.7%) of cases . 3D average examination time was 5.9 minutes compared to 9.2 minutes in the 2D technique. Follicles in volume range of (2-5ml) at the of hCG administration were statistically significant correlation to the retrieved mature oocytes with an explained variation percentage of (29%). Follicular volume of 5ml as cutoff was representative to the number of mature oocytes retrived . Conclusion: 3D ultrasound follicular monitoring is a time saving technique , provide a method of image quality control and create opportunities for developing new HCG administration criteria based on the follicular volume. |
