Klebsiella pneumonia in Boer goats is a multifactorial disease required a special care for good, active and rapid treatment. This study aimed to compare the therapeutic efficacy of three antibiotics (Tulathromycin, Florfenicol and Amoxicillin) in treatment of klebsiella pneumonia in Boer goat. This study was carried out on 45 diseased pneumonic Boer goats suffered from respiratory distress that were divided into three groups (each of 15) according to the type of the antibiotic used (Tulathromycin group, Florfenicol group and Amoxicillin group). All Boer goats were examined from 0 day before treatment and on the 1st, 3rd, 5th and 7th days post treatment. The results revealed a clinical recovery of 12 cases after first dose and 3 cases after the second dose of treatment with tulathromycin. Treatment with florfenicol revealed a clinical recovery of 11 cases after first dose and 4 cases recovered after the second dose. Treatment with amoxicillin showed recovery of 9 cases after the first dose, 3 cases recovered after the second dose and the other 3 cases required a third dose to be completely recovered. The results of hematology, serum biochemicals and pulmonary function tests revealed improvement of most of parameters from the 3rd day of treatment by tulathromycin and florfenicol. However, treatment by amoxicillin restored the parameters from the 5th day and may be extended to the 7th day of treatment. Isolates were subcultured and confirmed as K. pneumonia using standard microbiology techniques.The results were confirmed by antibiotic sensitivity test against klebsiella which was highly sensitive to tulathromycin, sensitive to florfenicol and less sensitive to amoxicillin. We conducted that tulathromycin has a better efficacy than florfenicol and amoxicillin in treatment of Boer goats affected with klebsiella pneumonia. |
