Coronary artery bypass surgery (CABG) in high risk patients is associated with high postoperative morbidity and mortality. Resting Heart System was developed to reduce the side effects of the conventional extracorporeal circulation machine.
Methods:
Prospective study to evaluate the outcome of elective beating CABG in high risk patients with the help of the Resting Heart System.
Results
116 patients were enrolled in the study, 59 in Resting Heart (Groups I) and 57 in CECC (Group II). The ejection fraction (EF) was not statistically significantly difference in 28.26±4.23% in I versus 27.00±4.81in% II, P= 0.13. EURO SCORE was 14.08±2.25 in I versus 14.61±2.37in II, P =0.22. No significant difference between both Groups regarding the operative data. The Ventilation time was not was not statistically significantly difference in Group I 12.20±3.16hours versus 14.01±3.07 hours in II, P =0.002. No statistical significance difference in Chest tube drainage it was 452.37±269.82ML in I versus 673.68±392.81ML in II, P =0.001. There was significant statistical difference regarding blood products transfusion, Packed RBCS transfusion was 0. 35±.1.14 units in I versus 1.00±1.39 units in II, P 0.04,Fresh frozen plasma (FFP) transfusion 1.00±2.20 units in I versus 1.50±2.20 units in II, P= 0.04)while platelets transfusion was 0.45±1.43 units in I versus 1.50±3.27 units in II, P= 0.02. In group I two patients were re-opened for bleeding (3.38%) versus three patients (5.26%) in Group II, P =0.29. Maximum Troponin level was 2.58±1.05 ng/mL in I versus 2.81±0.78 ng/mL in II, P =0.68. Mean ICU stay was 52.15±21.97hours in I versus73.47±59.47 in II hours, P =0.01. Two patients (3.38%) in I had postoperative wound infection versus 3 patients (5.26%) in II, P =0.38. Hospital stay was 7.76±0.93 days in I versus 8.36±1.26days in II, P =0.004. 30 days mortality was two patients died in I (3.38%) versus two patients (3.50%) in II, P =0.68.
Conclusion:
Beating CABG with Resting Heart system is well tolerated in high risk patients than conventional CPB.
Keywords: CABG, High risk, MECC.
|
