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Prof. Mohamed Sayed Abd el-Rhman Sayed Behalo :: Publications: |
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| Title: | Synthesis of quinazoline derivatives as potential antimicrobial agents, confernce 2015, The role ofApplied Science in Development and Social services |
| Authors: | Mohamed S. Behalo*, Abdelmotaal Abdelmajeid*, Aly A. Aly, Kaouser A. Hebash and Enas A. Mohamed |
| Year: | 2015 |
| Keywords: | Benzoxazinone, quinazolinone, amino acids, antimicrobial activity. |
| Journal: | The role ofApplied Science in Development and Social services |
| Volume: | 1 |
| Issue: | 1 |
| Pages: | 15-22 |
| Publisher: | Benha University, Faculty of Science |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Mohamed Sayed Abd el-Rhman Sayed Behalo_paper 3.pdf |
| Supplementary materials | Not Available |
| Abstract: |
An efficient synthesis of substituted quinazoline derivatives was achieved from the reaction of 2-((1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)methyl)-4H-benzo[d][1,3] oxazin-4-one (3) as a reactive starting material with variety of nucleophilic reagents. The Structural formula of all derivatives were confirmed and characterized by elemental analysis and spectral data. Some of the synthesized compounds were also screened for their antibacterial and antifungal activities and compared with standard drugs. Most of the tested compounds showed potent to weak antimicrobial activities. |
