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Prof. Mohamed Sayed Abd el-Rhman Sayed Behalo :: Publications: |
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| Title: | Regioselective synthesis, antitumor and
antioxidant activities of some 1,2,4-triazole
derivatives based on 4-phenyl-5-(quinolin-8-
yloxy)methyl-4H-1,2,4-triazole-3-thiol |
| Authors: | M. S. Behalo, M. S. Amine & I. M. Fouda |
| Year: | 2016 |
| Keywords: | Quinoline; triazole; pyrazole; thiazole; antitumor; antioxidant |
| Journal: | PHOSPHORUS, SULFUR, AND SILICON |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Taylor, Francis |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Mohamed Sayed Abd el-Rhman Sayed Behalo_triazole.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Regioselective synthesis of sometriazole derivatives 4–18 was achieved fromthe versatile, readily accessible 4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol/thione 3. The structures of the newly synthesized products were confirmed and characterized by IR, 1H NMR, 13C NMR, and mass spectral studies. Most of the synthesized compounds were evaluated for their antitumor and antioxidant activities and demonstrated potent to weak activities. |
