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Prof. Mohamed Mohamed Soliman Ahmed :: Publications:

Title:
No Alteration in Serum Leptin Levels during Acute Endotoxemia in Sheep
Authors: -Mohamed Soliman, Ibrahim fattouh; Shawky AbdelHady; Kimura K and Saito M
Year: 2001
Keywords: Not Available
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: International
Paper Link: Not Available
Full paper Mohamed Mohamed Soliman _my first paper.pdf
Supplementary materials Not Available
Abstract:

To determine the role of leptin in endotoxin-induced anorexia in ruminants, circulating leptin levels were measured during acute experimental endotoxemia in sheep. Injection of bacterial lipopolysaccharide(450 ng/kg, i.v.)induced anorexia accompanied with fever and increases in serum levels of cortisol, insulin and glucose which are known to stimulate leptin secretion in rodent and human, while it did not affect serum leptin levels at all. These results indicate that serum leptin levels in sheep during acute endotoxemia are differentially regulated from those in rodent and human, and that leptin might not be involved in the endotoxin-induced anorexia in sheep.

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