| You are in:Home/Publications/Synthesis, characterization and antitumour activity of Copper (II) complexes of some phosphonates | |
Prof. Mohamed Mohamed Soliman Ahmed :: Publications: |
|
| Title: | Synthesis, characterization and antitumour activity of Copper (II) complexes of some phosphonates |
| Authors: | 10. Ahmed I. Hanafy, Omar M. Ali, Zeinhom M. El-Bahy and Mohamed Mohamed Soliman |
| Year: | 2015 |
| Keywords: | Not Available |
| Journal: | International Journal of Scientific and Research Publications |
| Volume: | 5 |
| Issue: | 5 |
| Pages: | 15 |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | |
| Full paper | Mohamed Mohamed Soliman Ahmed _Phosphonate paper 2015.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Copper (II) complexes of three phosphonate ligands were prepared and fully characterized by elemental analysis, spectral and thermal studies. The IR spectral data showed that the phosphonate compounds behave as bidentate ligands coordinating to the copper ion through the P=O and NH groups. The electronic spectroscopic data support a distorted octahedral geometry around copper ion. The activity of the phosphonate ligands and their copper (II) complexes as small molecules were investigated towards DNA cleavage. The phosphonate ligands showed no activity, while the copper complexes showed DNA cleavage. The copper (II) complex of Diphenyl (3-hydroxyphenylamino)(2-hydroxyphenyl)methylphosphonate |
