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Prof. Mossad Gamal El-Din A. EL-SAYED :: Publications: |
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| Title: | Pharmacokinetic interperatation of antibiotics in camels.
Archives Internationals de pharmacodynamie et de therapie 261:186-189.
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| Authors: | A.Y. I. El-Gendi, M. G. A. El-Sayed and A. Z, Hussin |
| Year: | 1983 |
| Keywords: | Pharmacokinetic , antibiotics , camels. |
| Journal: | Archives Internationals de pharmacodynamie et de therapie |
| Volume: | 261 |
| Issue: | Not Available |
| Pages: | 186-189 |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Not Available |
| Supplementary materials | Not Available |
| Abstract: |
Evaluation of the pharmacokinetic properties of 4 antibiotics: penicillin-G (P), streptomycin (S), chloramphenicol (C) and oxytetracycline (O) was performed in groups of camels following a single i.m. injection of therapeutic doses, i.e. 6000 IU, 10, 4 and 3 mg/kg b.wt., respectively. The concentrations of these antibiotics in serum were determined by microbiological assay methods. The highest serum concentrations were reached after 0.42, 1.44, 4.02 and 0.94 hr for P, S, C, and O respectively with corresponding t 1/2 alpha values of 0.12, 0.28, 1.48 and 0.17 hr and t 1/2 beta values of 1.09, 8.28, 6.20 and 7.00 hr. |
